切换至 "中华医学电子期刊资源库"

中华卫生应急电子杂志 ›› 2020, Vol. 06 ›› Issue (04) : 209 -213. doi: 10.3877/cma.j.issn.2095-9133.2020.04.003

所属专题: 经典病例 文献

论著

94例武汉方舱医院新型冠状病毒肺炎患者临床特点分析
任慧娟1, 雷憾2, 孙贵新3, 李慧1, 白建文4, 唐伦先4,()   
  1. 1. 200120 上海,同济大学附属东方医院急诊内科;200120 上海,中国国际应急医疗队(上海)
    2. 200120 上海,同济大学附属东方医院呼吸科;200120 上海,中国国际应急医疗队(上海)
    3. 200120 上海,同济大学附属东方医院急诊外科;200120 上海,中国国际应急医疗队(上海)
    4. 200120 上海,同济大学附属东方医院急诊内科
  • 收稿日期:2020-03-13 出版日期:2020-08-18
  • 通信作者: 唐伦先
  • 基金资助:
    上海市重中之重重点专科(重症医学)项目(2017ZZ02017); 上海市浦东新区卫计委临床高峰学科(急危重症)项目(PWYgf2018-05); 上海市浦东新区卫计委领先人才项目(PWRI2019-05)

Clinical characteristics of 2019 novel coronavirus pneumonia in a mobile cabin hospital in Wuhan: analysis of 94 cases

Huijuan Ren1, Han Lei2, Guixin Sun3, Hui Li1, Jianwen Bai4, Lunxian Tang4,()   

  1. 1. Department of Emergency Medicine, Shanghai East Hospital Tongji University, Shanghai 200120, China; China International Emergency Medical Team (Shanghai), Shanghai 200120, China
    2. Department of Respiratory Medicine, Shanghai East Hospital Tongji University, Shanghai 200120, China; China International Emergency Medical Team (Shanghai), Shanghai 200120, China
    3. Department of Trauma, Shanghai East Hospital Tongji University, Shanghai 200120, China; China International Emergency Medical Team (Shanghai), Shanghai 200120, China
    4. Department of Emergency Medicine, Shanghai East Hospital Tongji University, Shanghai 200120, China
  • Received:2020-03-13 Published:2020-08-18
  • Corresponding author: Lunxian Tang
  • About author:
    Corresponding author: Tang Lunxian, Email:
引用本文:

任慧娟, 雷憾, 孙贵新, 李慧, 白建文, 唐伦先. 94例武汉方舱医院新型冠状病毒肺炎患者临床特点分析[J]. 中华卫生应急电子杂志, 2020, 06(04): 209-213.

Huijuan Ren, Han Lei, Guixin Sun, Hui Li, Jianwen Bai, Lunxian Tang. Clinical characteristics of 2019 novel coronavirus pneumonia in a mobile cabin hospital in Wuhan: analysis of 94 cases[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2020, 06(04): 209-213.

目的

收集分析方舱医院新型冠状病毒肺炎(COVID-19)确诊患者的特点,指导社区COVID-19的早识别、早筛查和早诊断。

方法

回顾性分析2020年2月7日至3月7日于武汉东西湖方舱医院感染病区就诊的94例COVID-19轻症确诊患者的病历资料,其中男性82例,女性12例;年龄17~69岁,平均(46.01±12.35)岁。以患者鼻咽拭子2019-nCoV核酸检测结果阳性为确诊日期,收集并分析患者的流行病学特征、潜伏期以及临床表现等。

结果

92例(97.9%)患者有可疑接触史,5例(5.3%)为无症状感染者。所有患者自接触可疑患者到出现临床症状时间为1~16 d,自出现临床症状到确诊时间为1~30 d。不同月份发病患者自出现临床症状到确诊的时间不尽相同:12月份(1例)为14 d;1月份(60例)为1~30 d;2月份(28例)为1~17 d。患者入住方舱医院的平均时间(20.31±5.05)d,所有患者自出现临床症状到呼吸道病毒核酸转阴时间为9~44 d。63例(67.0%)出现发热,45例(47.8%)出现干咳,25例(26.6%)出现乏力等。

结论

2019-nCoV感染患者临床症状没有特异性,常表现为发热、干咳、乏力,对于有类似表现并有可疑流行病学患者应尽早启动2019-nCoV核酸检测的筛查流程,早期发现可疑患者,并尽快就诊于方舱医院等感染病区。

Objective

To collect and analyze the case characteristics of 2019 novel coronavirus (COVID-19) patients admitted to the mobile cabin hospitals, to guide the early identification and screening as well as early diagnosis of COVID-19 in the community.

Methods

The medical records were retrospectively analyzed in 94 patients enrolled in the Wuhan Dongxihu Mobile Cabin Hospital from February 7 to March 7, 2020, including 82 males and 12 females, aged 17 to 69 years, with an average age of (46.01±12.35) years. the patient’s nasopharyngeal swab was taken for 2019-nCoV nucleic acid test; positive date for the diagnosis, the patient’s epidemiological characteristics, latency and clinical manifestations were collected and analyzed.

Results

92 patients (97.9%) had a history of suspected contact, and 5 patients (5.3%) were asymptomatic. The time from contact with suspicious patients to the appearance of clinical symptoms was 1 to 16 days, and the time from the appearance of clinical symptoms to the diagnosis was 1 to 30 days. The time from onset of clinical symptoms to diagnosis in different period varied: 14 days in December (1 case); 1-30 days in January (60 cases); 1-17 days in February (28 cases). The average length of hospital stay of patients in the cabin hospital was (20.31±5.05) days. The time from showing clinical symptom to negative viral nucleic acid was 9 ~ 44 days in all patients. Among them, 63 cases (67.0%) developed fever, 45 cases (47.8%) developed dry cough, and 25 cases (26.6%) developed fatigue etc.

Conclusions

This study indicates that 2019-nCoV infection patients have no specific clinical symptoms, and often manifest as fever, dry cough, and fatigue. For patients with similar manifestations and suspicious epidemiology, the screening process for 2019-nCoV nucleic acid should be initiated as soon as possible, to detect suspicious patients early and improve screening efficiency, Confirmed patient should conduct further treatment as early as possible in infection treatment wards, such as the mobile cabin hospitals.

1
Chan JW, Yuan S, Kok KH,et al.A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster[J].Lancet,2020,395(10223):514-523.
2
Chi Zhang, Mei Wang.MRCA time and epidemic dynamics of the 2019 novel coronavirus[J/OL].bioRxiv[2020-01-31].

URL    
3
Wang R, Zhang X, Irwin DM, et al.Emergence of SARS-like Coronavirus poses new challenge in China[J].J Infect,2020,80(3):350-371.
4
Tang JW, Tambyah PA, Hui DSC.Emergence of a novel coronavirus causing respiratory illness from Wuhan, China[J].J Infect,2020,80(3):350-371.
5
Zhu N, Zhang D, Wang W,et al.A Novel Coronavirus from Patients with Pneumonia in China, 2019[J].N Engl J Med,2020,382(8):727-733.
6
Khan S, Ali A, Siddique R,et al.Novel coronavirus is putting the whole world on alert[J].J Hosp Infect,2020,104(3):252-253.
7
Luo GG, Gao SJ.Global health concerns stirred by emerging viral infections[J].J Med Virol,2020, 92(4):399-400.
8
Wu JT, Leung K, Leung GM.Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan,China:a modelling study[J].Lancet,2020,395(10225):689-697.
9
Zhao S, Lin Q, Ran J,et al.Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a data-driven analysis in the early phase of the outbreak[J].Int J Infect Dis,2020,92:214-217.
10
Shen MW, Peng ZH, Xiao YN.Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China[J/OL].bioRxiv[2020-01-25].

URL    
11
Riou J, Althaus CL.Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV),December 2019 to January 2020[J].Euro Surveill,2020,25(4):2000058.
12
Jonathan M.Read, Jessica R.E.Bridgen, Derek A.T.Cummings,et al.Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions[J/OL].medRxiv[2020-01-28].

URL    
13
杨涛,于晓娜,贺星星,等.新型冠状病毒肺炎早期临床表现及肺部影像学分析[J].中华急诊医学杂志,2020,29(3):341-345.
14
国家卫生健康委办公厅,国家中医药管理局办公室.关于印发新型冠状病毒肺炎诊疗方案(试行第六版)的通知[EB/OL].(2020-02-19)[2020-03-13].

URL    
15
Huang C, Wang Y, Li X,et al.Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J].Lancet,2020,395(10223):497-506.
16
Chen N, Zhou M, Dong X,et al.Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan,China:a descriptive study[J].Lancet,2020,395(10223): 507-513.
17
李妍,徐胜勇,杜铁宽,等.新型冠状病毒肺炎临床特点及筛查流程探讨[J].中华急诊医学杂志,2020,29(3):336-340.
[1] 李凯, 刘振东, 贾大洲, 李小磊, 王静成. 股骨粗隆间骨折术后非感染性发热因素及风险模型[J]. 中华关节外科杂志(电子版), 2022, 16(05): 547-554.
[2] 刘百岁, 倪霞, 王琴. 硬膜外分娩镇痛相关产时发热对母婴结局的影响[J]. 中华妇幼临床医学杂志(电子版), 2022, 18(05): 577-584.
[3] 刘铭, 闻赛, 李娜, 陈潇, 时玉雯, 王刚, 刘岚铮, 刘辉. 米氏克雷伯菌合并白色念珠菌感染致不明原因发热一例并文献复习[J]. 中华实验和临床感染病杂志(电子版), 2022, 16(01): 65-70.
[4] 王鹤, 胡岚, 方媚, 栗绍刚, 王超, 齐文杰. 北京地区输入性人粒细胞无形体病患者一例[J]. 中华实验和临床感染病杂志(电子版), 2022, 16(01): 60-64.
[5] 张龙辉, 杨仕明, 倪梦, 牛敬, 刘瑶, 兰洁, 唐棠. 国展中心方舱医院首批出舱新型冠状病毒感染者特征分析[J]. 中华肺部疾病杂志(电子版), 2022, 15(04): 571-573.
[6] 武秀权, 张磊, 吴霜, 郇宇, 何鑫, 鱼洋, 杜伟, 郭庆东, 费舟, 蒋晓帆. 日均发热次数对颅脑损伤伤情影响的临床意义[J]. 中华神经创伤外科电子杂志, 2021, 07(03): 137-140.
[7] 李雪珠, 谢剑锋, 李晓青, 夏泽燕, 鲁玲, 顾晓霞, 马绍磊, 黄英姿. 循环式筛查与五色区域分类模式在方舱医院管理中的应用[J]. 中华重症医学电子杂志, 2023, 09(03): 316-320.
[8] 李晓青, 夏泽燕, 黄英姿, 黄碧红, 赵雪红, 段培蓓, 王蓓, 田月香, 蔡英华, 高燕, 贾艳, 杨昕, 周静, 秦毅. 巨型方舱医院护理管理实践与体会[J]. 中华重症医学电子杂志, 2022, 08(03): 272-275.
[9] 黄英姿, 吴文忠, 占伊扬, 陆敏, 邱泽森, 鲁翔. 巨型方舱医院高效安全运维的实践经验——一个目标、双线协同、三个关键、四种模式[J]. 中华重症医学电子杂志, 2022, 08(03): 203-206.
[10] 辛彩焕, 熊辉. 非疫区36例布鲁菌病患者的临床特征及诊疗分析[J]. 中华临床医师杂志(电子版), 2023, 17(9): 927-931.
[11] 姚雄宇, 董秀哲, 李晓刚, 张恩浩, 侯国军. 布鲁菌病致前列腺炎合并脊柱炎一例并文献复习[J]. 中华临床医师杂志(电子版), 2023, 17(05): 624-626.
[12] 麻希洋, 吴荣贺, 潘兴飞, 陈敦金, 贺芳. 新型冠状病毒奥密克戎变异株流行期间孕产妇感染临床分析[J]. 中华产科急救电子杂志, 2023, 12(02): 103-108.
[13] 毛源, 张淑正, 郑伟, 李东阳, 曾敬富, 任婵君, 李慧源. 大规模新型冠状病毒核酸检测需求下气膜实验室多方合作运营经验总结[J]. 中华临床实验室管理电子杂志, 2023, 11(03): 167-174.
[14] 陈翀, 游冉冉, 王敏, 周豪杰. 单试剂HBsAg阳性、核酸检测阴性献血者的血液安全性评估[J]. 中华临床实验室管理电子杂志, 2023, 11(02): 95-98,104.
[15] 孙维杰, 翁跃颂, 沈驰斌, 韩阿祥, 刘旭峰, 徐灵, 陈雪琴. 方舱医院医学检验实验室建设运行探索[J]. 中华临床实验室管理电子杂志, 2022, 10(04): 242-245.
阅读次数
全文


摘要