| 1 |
Angus DC,，Linde-Zwirble WT,，Lidicker J，et al.Epidemiology of severe sepsis in the United States：analysis of incidence，outcome，and associated costs of care[J]. Crit Care Med，2001，29(7)：1303-1310.
|
| 2 |
Li W,，Wang M,，Zhu B，et al.Prediction of median survival time in sepsis patients by the SOFA score combined with different predictors[J]．Burns Trauma，2020(8)：tkz006.
|
| 3 |
Wang HE,，Shapiro NI,，Angus DC，et al.National estimates of severe sepsis in united states emergency departments[J]．Crit Care Med，2007，35(8)：1928-1936.
|
| 4 |
Fleischmann C,，Scherag A,，Adhikari NK，et al.Assessment of global incidence and mortality of hospital-treated sepsis. current estimates and limitations[J]．Am J Respir Crit Care Med，2016，193(3)：259-272.
|
| 5 |
Weng L,，Zeng XY,，Yin P，et al.Sepsis-related mortality in China：a descriptive analysis[J]．Intensive Care Med，2018，44(7)：1071-1080.
|
| 6 |
Rivers E,，Nguyen B,，Havstad S，et al.Early goal-directed therapy in the treatment of severe sepsis and septic shock[J]．N Engl J Med，2001，345(19)：1368-1377.
|
| 7 |
ProCESS Investigators, Yealy DM, Kellum JA，et al.A randomized trial of protocol-based care for early septic shock[J]．N Engl J Med，2014，370(18)：1683-1693.
|
| 8 |
De Backer D,，Dorman T．Surviving sepsis guidelines：a continuous move toward better care of patients with sepsis[J]．JAMA，2017，317(8)：807-808.
|
| 9 |
Dellinger RP,，Carlet JM,，Masur H，et al.Surviving sepsis campaign guidelines for management of severe sepsis and septic shock[J]．Crit Care Med，2004，32(3)：858-873.
|
| 10 |
Dellinger RP,，Levy MM,，Carlet JM，et al.Surviving sepsis campaign：international guidelines for management of severe sepsis and septic shock：2008[J]．Intensive Care Med，2008，34(1)：17-60.
|
| 11 |
Dellinger RP,，Levy MM,，Rhodes A，et al.Surviving sepsis campaign：international guidelines for management of severe sepsis and septic shock：2012[J]．Crit Care Med，201，41(2)：580-637.
|
| 12 |
Howell MD,，Davis AM.Management of sepsis and septic shock[J].2017，317(8)：847-848.
|
| 13 |
Rhodes A,，Evans LE,，Alhazzani W，et al.Surviving sepsis campaign：International guidelines for management of sepsis and septic shock：2016[J]．Intensive Care Med，2017，43(3)：304-377.
|
| 14 |
ProCESS Investigators，Yealy DM,，Kellum JA，et al.A randomized trial of protocol-based care for early septic shock[J]．N Engl J Med，2014，370(18)：1683-1693.
|
| 15 |
Mouncey PR,，Osborn TM,，Power GS，et al.Trial of early，goal-directed resuscitation for septic shock[J]．N Engl J Med，2015，372(14)：1301-1311.
|
| 16 |
Peake SL,，Delaney A,，Bailey M，et al.Goal-directed resuscitation for patients with early septic shock[J]．N Engl J Med，2014，371(16)：1496-1506.
|
| 17 |
Levy MM,，Evans LE,，Rhodes A．The surviving sepsis campaign bundle：2018 update[J]．Crit Care Med，2018，46(6)：997-1000.
|
| 18 |
Evans L,，Rhodes A,，Alhazzani W，et al.Surviving sepsis campaign：international guidelines for management of sepsis and septic shock 2021[J]．Crit Care Med，2021，47(11)：e1063-e1143.
|
| 19 |
Islam MM,，Nasrin T,，Walther BA，et al.Prediction of sepsis patients using machine learning approach：a meta-analysis[J]．Comput Methods Programs Biomed，2019(170): 1-9.
|
| 20 |
Cecconi M,，Hernandez G,，Dunser M，et al.Fluid administration for acute circulatory dysfunction using basic monitoring：narrative review and expert panel recommendations from an ESICM task force[J]．Intensive Care Med，2019，45(1)：21-32.
|
| 21 |
Lara B,，Enberg L,，Ortega M，et al.Capillary refll time during fuid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality[J]．PLoS One，2017，12(11)：e0188548.
|
| 22 |
Seymour CW,，Gesten F,，Prescott HC，et al.Time to treatment and mortality during mandated emergency care for sepsis[J]．N Engl J Med，2017，376(23)：2235-2244.
|
| 23 |
Sterling SA,，Miller WR,，Pryor J，et al.The impact of timing of antibiotics on outcomes in severe sepsis and septic shock：a systematic review and meta-analysis[J]．Crit Care Med，2015，43(9)：1907-1915.
|
| 24 |
Liu VX,，Fielding-Singh V,，Greene JD，et al.The timing of early antibiotics and hospital mortality in sepsis[J]．Am J Respir Crit Care Med，2017，196(7)：856-863.
|
| 25 |
Alam N,，Oskam E,，Stassen PM，et al.Prehospital antibiotics in the ambulance for sepsis：a multicentre，open label，randomized trial[J]．Lancet Respir Med，2018，6(1)：40-50.
|
| 26 |
Klein Klouwenberg PM,，Cremer OL,，van Vught LA，et al.Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission：a cohort study[J]．Crit Care，2015，19(1)：319.
|
| 27 |
Tidswell R,，Parker T,，Brealey D，et al.Sepsis-the broken code how accurately is sepsis being diagnosed？[J]．J Infect，2020，81(6)：e31-e32.
|
| 28 |
Mitchell KH,，Carlbom D,，Caldwell E，et al.Volume overload：prevalence，risk factors，and functional outcome in survivors of septic shock[J]．Ann Am Thorac Soc 2015，12(12)：1837-1844.
|
| 29 |
Moss SR,，Prescott HC.Current controversies in sepsis management[J]．Semin Respir Crit Care Med，2019，40(5)：594-603.
|
| 30 |
Bourgoin A,，Leone M,，Delmas A，et al.Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function[J]．Crit Care Med，2005，33(4)：780-786.
|
| 31 |
Macdonald SPJ,，Taylor DM,，Keijzers G，et al.Restricted fluid resuscitation in sepsis-associated hypotension(REFRESH)：study protocol for a pilot randomized controlled trial[J]．Trial，2017，18(1)：399.
|