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中华卫生应急电子杂志 ›› 2020, Vol. 06 ›› Issue (03) : 136 -141. doi: 10.3877/cma.j.issn.2095-9133.2020.03.002

所属专题: 文献

论著

新型冠状病毒肺炎疫情形势下的急诊应对策略
杨贞文1,(), 谢劲军2, 刘桂荣3, 揭育胜4, 李刚4   
  1. 1. 514700 广东梅州,中山大学附属第三医院粤东医院急诊医学科
    2. 514700 广东梅州,中山大学附属第三医院粤东医院医学影像科
    3. 514700 广东梅州,中山大学附属第三医院粤东医院检验科
    4. 510620 广东广州,中山大学附属第三医院感染性疾病科
  • 收稿日期:2020-02-24 出版日期:2020-06-18
  • 通信作者: 杨贞文

Emergency response strategy to Corona virus disease 2019 epidemic

Zhenwen Yang1,(), Jinjun Xie2, Guirong Liu3, yusheng Jie4, Gang Li4   

  1. 1. Emergency Department, the Third Affiliated Hospital of Sun Yat-sen University, Meizhou 514700, China
    2. Department of Medical Imaging, the Third Affiliated Hospital of Sun Yat-sen University, Meizhou 514700, China
    3. Clinical Laboratory, the Third Affiliated Hospital of Sun Yat-sen University, Meizhou 514700, China
    4. Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510620, China
  • Received:2020-02-24 Published:2020-06-18
  • Corresponding author: Zhenwen Yang
  • About author:
    Corresponding author: Yang Zhenwen, Email:
引用本文:

杨贞文, 谢劲军, 刘桂荣, 揭育胜, 李刚. 新型冠状病毒肺炎疫情形势下的急诊应对策略[J]. 中华卫生应急电子杂志, 2020, 06(03): 136-141.

Zhenwen Yang, Jinjun Xie, Guirong Liu, yusheng Jie, Gang Li. Emergency response strategy to Corona virus disease 2019 epidemic[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2020, 06(03): 136-141.

目的

分析中山大学附属第三医院粤东医院发热门诊接诊病例和确诊住院的新型冠状病毒肺炎(COVID-19)患者临床特征,为COVID-19早发现、早诊断提供临床依据,探索当前疫情形势下的急诊应对策略。

方法

回顾性分析中山大学附属第三医院粤东医院2020年1月25日至2020年2月6日发热预检分诊处分诊的537例临床资料和分诊结果;同时对收住院的7例已确诊的COVID-19患者,就其流行病学资料,入院时临床资料、影像学检查、实验室检查,以及新型冠状病毒(2019-nCoV)核酸检测阳性结果(咽拭子+大便)进行回顾性分析。

结果

发热预检分诊处共分诊537例,其中分诊至普通发热门诊469例(占87.3%),均行胸部CT检查,影像学表现为肺部炎症37例(占7.8%),全部病例经咽拭子和大便2019-nCoV核酸检测为阴性;分诊至特殊发热门诊68例(占12.7%),其中负压救护车接回41例,确诊6例;自行来院就诊27例,确诊1例,确诊患者占特殊发热门诊患者10.3%。确诊患者均与武汉疫源区有关(包括武汉疫源区居住史或与疫源区人员密切接触史),临床表现主要为发热和(或)呼吸道症状(咽痛,咳嗽、咳痰,胸闷,声嘶,鼻塞、咽干,乏力等),入院时病程1~8 d,平均3.7 d;全部患者胸部CT扫描均表现肺部炎症,其中双肺肺炎占71.42%;仅1例患者外周血白细胞计数、淋巴细胞比例、淋巴细胞绝对值和C反应蛋白异常;7例COVID-19患者咽拭子2019-nCoV核酸检测均为阳性,4例同时伴大便2019-nCoV酸检测阳性,大便核酸检测阳性时间均晚于咽拭子核酸检测阳性1~7 d,平均3.25 d。

结论

根据流行病学史进行急诊快速预检分诊,在抗击COVID-19疫情中体现出接诊效率高,可最大程度减少误诊和预防院内交叉感染,值得推广应用。

Objective

To analyze the clinical features of Corona virus disease 2019 (COVID-19) in the Third Affiliated Hospital of Sun Yat-sen University, to provide clinical evidence for early detection and diagnosis of COVID-19 and to explore the emergency response strategy under the current epidemic situation.

Methods

Retrospective analysis was made on the clinical data and triage results in 537 cases of pre-examination and triage of fever in the Third Affiliated Hospital of sun Yat-sen University from January 25, 2020 to February 6, 2020; meanwhile, 7 COVID-19 cases were collected. The novel corona virus nucleic acid test results (throat swab plus stool) were retrospectively analyzed on the basis of epidemiological data, clinical data, imaging examination, laboratory examination and new corona virus nucleic acid test.

Results

537 cases were divided in the pre-examination and triage desk of fever clinic: 469 cases (87.3%) were divided into the general fever clinic. All patients underwent chest CT examination, and the imaging findings were pulmonary inflammation in 37 cases (7.8%). The novel coronavirus nucleic acid was negative in all swabs and stool. 68 cases (12.7%) were divided into the special fever clinics; 41 cases were received by negative pressure ambulance and 6 cases were confirmed; 27 cases were sent to the hospital and 1 case was confirmed. The confirmed cases accounted for 10.3% of outpatients with special fever. The confirmed cases were all related to the epidemic area of Wuhan, including the history of living in the epidemic area of Wuhan or the history of close contact with people in the epidemic area. The main clinical manifestations were fever and/or respiratory symptoms (sore throat, cough, expectoration, chest tightness, hoarseness, stuffy nose, dry throat, fatigue, etc.). The duration of hospitalization was 1-8 days (mean 3.7 days). Chest CT showed pulmonary inflammation in all cases, of which pneumonia of both lobes accounted for 71.42%. Only one patient had abnormal peripheral blood leukocyte count, lymphocyte proportion, lymphocyte absolute value and C-reactive protein; 7 cases of COVID-19 and throat swabs were positive for the virus. The novel coronavirus with stool was positive in 4 cases and the positive time of stool nucleic acid detection was later than that of throat swab 1 - 7 days, with an average of 3.25 days.

Conclusion

Rapid pre-examination and triage based on the epidemiological history of the disease have been shown to be highly effective in combating COVID-19, minimizing misdiagnosis and preventing nosocomial cross infection, which is worth popularizing.

图1 流行病学史分诊章
表1 7例COVID-19患者入院时临床资料
图2 COVID-19患者胸部CT影像学表现
表2 7例COVID-19患者实验室检验结果
表3 7例COVID-19患者首次2019-nCoV核酸检测(咽拭子+大便)阳性情况
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