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中华卫生应急电子杂志 ›› 2020, Vol. 06 ›› Issue (03) : 162 -165. doi: 10.3877/cma.j.issn.2095-9133.2020.03.006

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新型冠状病毒感染、抗感染措施及治疗
丁文玉1, 何聪芬1,()   
  1. 1. 100048 北京,北京工商大学理学院
  • 收稿日期:2020-03-06 出版日期:2020-06-18
  • 通信作者: 何聪芬

Novel coronavirus infection, anti-infection measures and treatment

Wenyu Ding1, Congfeng He1()   

  • Received:2020-03-06 Published:2020-06-18
  • Corresponding author: Congfeng He
引用本文:

丁文玉, 何聪芬. 新型冠状病毒感染、抗感染措施及治疗[J]. 中华卫生应急电子杂志, 2020, 06(03): 162-165.

Wenyu Ding, Congfeng He. Novel coronavirus infection, anti-infection measures and treatment[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2020, 06(03): 162-165.

表1 7种HCoV分类
图1 2019新型冠状病毒(2019-nCoV)
表2 各种抗COVID-19药物优缺点对比分析
1
Fehr AR, Perlman S.Coronaviruses:an overview of their replication and pathogenesis[J].Methods Mol Biol,2015,(1282):1-23.
2
陈云欢,伍严安.两种新型人冠状病毒HCoV-NL63和HCoV-HKU1的研究进展[J].医学综述,2010,16(17):2596-2598.
3
Guan Y, Zheng BJ, He YQ,et al.Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China[J].Science,2003,302(5643):276-278.
4
刘培林,史蕾,顾大勇,等.人冠状病毒HCoV-HKU1研究进展[J].中国公共卫生,2017,33(8):1264-1266.
5
Chafekar A, Fielding BC.MERS-CoV:Understanding the latest human coronavirus threat[J].Viruses,2018,10(2):93.
6
Lu R, Zhao X, Li J,et al.Genomic characterisation and epidemiology of 2019 novel coronavirus:implications for virus origins and receptor binding[J].Lancet,2020,395(10224):565-574.
7
Zhou P, Yang XL, Wang XG,et al.A pneumonia outbreak associated with a new coronavirus of probable bat origin[J].Nature, 2020,579(7798):270-273.
8
李鹤,谭晓川,姜栋,等.冠状病毒及其治疗药物研究进展[J].中国药学杂志,2020,55(4):284-292.
9
Heurich A, Hofmann-Winkler H, Gierer S,et al.TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein[J].J Virol,2014,88(2):1293-1307.
10
Hamming I, Timens W, Bulthuis ML,et al.Tissue distribution of ACE2 protein,the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis[J].J Pathol,2004,203(2):631-637.
11
Yan RH, Zhang YY, Guo YY,et al.Structural basis for the recognition of the 2019-nCoV by human ACE2[J/OL].bioRxiv,2020 [2020-02-20].

URL    
12
搜狐.新冠病毒侵染人体那一刻发生了什么?西湖大学深入破解 [EB/OL].(2020-02-23)[2020-03-06].

URL    
13
Wrapp D, Wang N, Corbett KS,et al.Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation[J].Science,2020,367(6483):1260-1263.
14
国家卫生健康委办公厅,国家中医药管理局办公室.关于印发新型冠状病毒肺炎诊疗方案(试行第七版)的通知[EB/OL].(2020-03-04)[2020-03-06].

URL    
15
刘千勇,王晓良.新型冠状病毒(2019-nCoV)的靶向药物研究策略[J].药学导报,2020,55(2):181-188.
16
陈祝君,边原,杨勇,等.新型冠状病毒感染性肺炎中成药的合理使用[J/OL].医药导报,2020[2020-02-11].

URL    
17
中国新闻网.李兰娟团队:阿比朵尔、达芦那韦能有效抑制冠状病毒[EB/OL].(2020-02-04)[2020-03-06].

URL    
18
人民日报、中国网.国务院联防联控机制新闻发布会:磷酸氯喹治疗新冠肺炎具有一定疗效[EB/OL].(2020-02-17).[2020-03-06].

URL    
19
优酷.抗体才是治疗新冠状病毒最好药物,武汉已从治愈患者身体成功提出[EB/OL].(2020-02-15)[2020-03-06].

URL    
20
熊堉,蒋敏,边原,等.探索利巴韦林治疗新型冠状病毒肺炎的有效性和安全性:基于既往冠状病毒治疗的总结[J/OL].医学导报,2020[2020-02-13].

URL    
21
Knowles SR, Phillips EJ, Dresser L,et al.Common adverse events associated with the use of ribavirin for severe acute respiratory syndrome in Canada[J].Clin Infect Dis,2003,37(8):1139-1142.
22
Sheahan TP, Sims AC, Leist SR,et al.Comparative therapeutic efficacy of remdesivir and combination lopinavir,ritonavir,and interferon beta against MERS-CoV[J].Nat Commun,2020,11(1):222.
23
Gassen NC, Niemeyer D, Muth D,et al.SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection[J].Nat Commun,2019,10(1):5770.
24
Jones ST, Cagno V, Janeček M,et al.Modified cyclodextrins as broad-spectrum antivirals[J].Sci Adv,2020,6(5):eaax9318.
25
中国军网综合.大好消息!目前新冠肺炎相关研究已获诸多成果[EB/OL].(2020-03-04).[2020-03-06]

URL    
26
Tang XL, Wu CC, Li X,et al.On the origin and continuing evolution of SARS-CoV-2[J].NSR,2020[2020-03-03].

URL    
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