Objective to explore the senior pre-hospital and hospital early airway based on the effect of acute severe craniocerebral injury treatment.

Between January 2013 and January 2016 chifeng institute affiliated hospitals of acute severe craniocerebral injury patients (GCS score eight minutes or less) of 72 cases were randomly divided into pre-hospital group (38 cases) and hospital group (34 cases) and comparison of two groups of patients with respiratory physiology change and prognosis.

the two groups before and after endotracheal intubation respiratory physiology indexes improved to varying degrees, PaO before intubation (58.61+ /-14.53-58.61-14.68), after intubation PaO (78.91+ /-14.61-83.17-13.94) and PaCO₂ before intubation (85.33+ /-5.41-85.33-7.01), after intubation PaCO₂ (92.01+ /-4.21-94.84-3.2) before intubation SPO₂ (85.33+ /-5.41-85.33-7.01), after intubation SPO₂ (92.01+ /- 4.21-94.85-3.21) HR before intubation (95.82+ /-13.09-95.82-6.51), HR after intubation (84.65+ /-10.44-84.65-5.22), before intubation RR (21.21+ /- 5.51-21.21-6.42), after intubation RR (19.21+ /- 3.91-18.49-5.21) each index were improved significantly after intubation, compare the difference was statistically significant (P<0.05); Two groups in terms of good prognosis rate comparative differences are statistically significant (P<0.05).

Pre-hospital early endotracheal intubation can improve oxygenation of patients with acute severe craniocerebral injury, reduce or avoid the happening of hypoxemia, avoid or reduce the occurrence of aspiration, reduce the incidence of aspiration pneumonia, improve the prognosis of patients with good rates.