To explore the pre-hospital application of shock index （SI）as a predictor of the risk in trauma patients.
Methods
A retrospective study was conducted on trauma patients treated before hospital from January 1， 2022 to December 31， 2023.For trauma patients aged over 18 years and met the inclusion criteria， the shock index was calculated according to blood pressure and heart rate at the prehospital emergency site， and the patient's condition was evaluated according to the pre-hospital shock index score， so as to judge whether the shock index could judge the condition trend of trauma patients.
Results
A total of 3，493 patients were enrolled in this study， including 2，086 males （59.72%） and 1，407 females（40.28%）， aged 14-88 years， with average of （64.5±15.16） years.Blunt trauma and penetrating trauma accounted for 90.98% and 9.02% of all trauma cases， respectively.Generally speaking， 87.20% of patients were caused by traffic accidents， and other reasons only accounted for 12.80%.The proportions of low （≤0.4），normal （0.4＜SI＜1.0） and high （≥1.0） SI groups were 6.90%， 86.37% and 6.73% respectively.Among all patients， a total of 77（2.20%） died within 24 hours.Compared with the low SI group （SI≤0.4）， the mortality of patients in normal （0.4＜SI＜1.0） group was significantly lower （P＜0.01）， while the mortality of patients in high（≥1.0） SI group was significantly higher （P=0.03）.
Conclusion
The mortality of trauma patients with normal pre-hospital SI （0.4＜SI＜1.0） is lower than that of patients with abnormal pre-hospital SI （≥1.0 or≤0.4）within 24 hours， and the mortality of patients with high SI is significantly increased.
To observe the effect of quality control circle and interactive health education in children with severe bronchial asthma.
Methods
A total of 152 children with severe bronchial asthma admitted to the Third Affiliated Hospital of Nanjing Medical University from January 2022 to May 2024 were selected as the research subjects； there were 82 males and 70 females， aged 5～11 years， with mean （8.10±2.00） years.They were divided into control group （routine care， n=76） and observation group （interactive health education， n=76）.FeNO， pulmonary function （FVC， FEV1， PEF）， psychological state （HAMD，HAMA）， caring ability （MCEM）， and disease control effect （C-ACT） were compared.
Results
The level of FeNO in two groups at 1 month and 3 months was lower than that before intervention （P＜0.05）.The FeNO levels of the children in the observation group were lower than those in the control group after 1 month and 3 months of intervention （P＜0.05）.After intervention， the scores of FVC， FEV1， PEF and parents' MCEM scores were higher than those before intervention （P＜0.05）.After intervention， FVC， FEV1， PEF and parents'MCEM scores of the observation group were higher than those of the control group （P＜0.05）.HAMD and HAMA scores after intervention were lower than those before intervention （P＜0.05）.After intervention，HAMD and HAMA scores in the observation group were lower than those in the control group （P＜0.05）.After intervention， the C-ACT score of the observation group was higher than that of the control group （P＜0.05）.
Conclusions
The corresponding application of quality control circle and interactive health education in children with severe bronchial asthma can improve the lung function of children， reduce the level of FeNO，improve the psychological state of children and the ability of parents to take care of children， and thus increase the control effect of severe bronchial asthma.
To investigate the current status of pre-hospital emergency knowledge，attitudes， beliefs and practices （KABP） among non-medical college students， providing a basis and direction for the development of campus emergency training programs.
Methods
A random sample of non-medical college students from four institutions in Kunshan was surveyed using a self-designed questionnaire.Group t-tests and mean analysis were employed to examine the influence of factors such as gender， education level，health status， and previous training experience on KABP.Interviews with campus administrators were conducted to gather information about campus emergency first-aid training and to identify influencing factors， with feasible recommendations for improvement.
Results
A total of 9，311 participants completed the survey， with females comprising 38.90%， a lower proportion than males.Among respondents， 30.20%had prior first-aid training experience， while 69.80% had no such experience.Of those with training， 21.34%had received it within the last three months， 2.90% within the last six months， and 5.96% within the last year.Regarding willingness to participate in future training， 67.73% expressed interest， while 33.27% were unwilling.The average scores for first-aid knowledge， attitudes， and behaviors were 14.60， 43.92， and 25.90，respectively.Of the 30 items analyzed， 23 were found to have significant correlations with prior training，while 7 were not.Multivariate logistic regression analysis revealed that gender， health status， education level，household registration， and prior training experience had statistically significant effects on first - aid knowledge， attitudes， and behaviors （P＜0.05）.
Conclusion
First-aid training among college students in Kunshan is inadequate， which is linked to a general lack of awareness regarding campus health emergency management.Overcoming the limitations of time， resources， and interaction space for students are crucial.Training programs should focus on life-saving knowledge and skills， prioritizing the assessment， recognition，and provision of first-aid for rare， critical， and specialized emergencies.These programs should aim to equip students with practical， success-promoting experiences.Non-medical college students possess strong first-aid knowledge and display positive attitudes and behaviors toward first-aid.They can be cultivated as key participants in both campus and societal emergency first-aid efforts， representing a valuable high-quality population for the effective implementation and transfer of first-aid training outcomes into real-world applications.
To compare the difference of data quality and early warning effectiveness of infectious diseases between manual attendance and intelligent attendance， in order to provide empirical reference for the construction of intelligent infectious disease syndromic surveillance.
Methods
Two primary schools A and B in a city were selected to collect absenteeism data for the 2021-2022 school year by the two methods： Face recognition attendance （standard： absence time ≥1 hour）， the all-cause absenteeism rates of grades 1-2 （DARL）， grades 3-6 （DARH） and the whole school （DARW1） were collected； School doctor attendance （standard： absent for a whole day）， the all-cause （DARW2） and sickness （DARW3）absenteeism rate of the whole school were collected.
Results
DARW2 and DARW3 comprised 32.6% and 25.2% of DARW1， respectively， and DARW3 comprised 77.3% of DARW2.In School A， DARW1 was significantly correlated with DARW2 （r=0.256， P＜0.001）， DARW1 was significantly correlated with DARW3（r=0.243， P＜0.001）， and DARW2 was significantly correlated with DARW3 （r=0.954， P＜0.001）； In School B，DARW1 and DARW2 （r=0.800，P＜0.001）， DARW1 and DARW3 （r=0.790，P＜0.001）， and DARW2 and DARW3 （r=0.964，P＜0.001） were also significantly related.The early warning sensitivity of DARL， DARH，DARW1， DARW2 and DARW3 was 97.0%， 95.3%， 100%， 100%， 100%， the specificity was 88.5%， 91.7%，81.8%， 80.3%， 78.4%， and the Yoden index was 85.5%， 87.0%， 81.8%， 80.3% and 78.4%， respectively.
Conclusions
Compared with manual attendance， smart attendance-based surveillance system has higher data quality and thus better surveillance accuracy.Moreover， adjusting absenteeism time and calculating absenteeism rate by grade segment could further improve the effectiveness of smart attendance-based surveillance system in early warning of infectious disease outbreaks.
To observe the therapeutic effect of recombinant human acidic fibroblast growth factor （rhaFGF） on acute wounds in diabetes mellitus （DM） mice， and to explore its possible underlying mechanisms in chronicity of acute DM wound.
Methods
Acute DM wound models were established in male C57 mice.The mice were divided into four groups： Con （n=17）， Con+rhaFGF （n=17）， DM（n=17）， and DM+rhaFGF （n=17）.rhaFGF （0.08 μg/cm²） or PBS was daily administered on wound surface for 14 days after wound creation.The wound healing rates were calculated in each group.On the 7th day after rhaFGF administration， the levels of IL-6 and TNF-α in serum and tissues of mice were detected by ELISA.Additionally， the expression of IL-1β， IL-18 and NLRP3 inflammatory-associated molecules （NLRP3， ASC，and Caspase-1） in the tissues were measured using Western blot analysis.
Results
From the 9th day after modeling， the wound healing rates observed in the DM group was significantly lower than those of the Con group （P＜0.05）.Additionally， the healing rates in the DM+ rhaFGF group was significantly higher than that in the DM group from the 7th day （P＜0.05）.On the 7th day after modeling， the levels of IL-6 and TNF-α in the DM group were significantly higher than those in the Con group.In contrast， the levels of these molecules in the DM + rhaFGF group were significantly lower than those in the DM group （P＜0.05）.The levels of NLRP3， ASC， caspase-1， IL-1β， and IL-18 in the tissues of the DM group were significantly higher than those in the Con group.In contrast， the levels of these molecules in the DM + rhaFGF group were significantly lower than those in the DM group （P＜0.05）.
Conclusion
RhaFGF promotes the healing of acute DM wounds by reducing the release of pro - inflammatory factors and preventing the transition from acute to chronic inflammation.This mechanism may be associated with the inhibition of NLRP3 in acute DM wounds.
