To investigate the efficacy of a modified respiratory support strategy on patients with chronic obstructive pulmonary disease (AECOPD) combined with type II respiratory failure.

Sixty-eight patients with AECOPD combined with type II respiratory failure who were admitted to the ICU of Huazhong University of Science and Technology Union Shenzhen Hospital in 2021-2023 were categorized into an intervention group (34 patients) and a control group (34 patients). Patients in the intervention group were treated with a modified respiratory support strategy that was dynamically adjusted to either high-flow oxygen therapy or noninvasive ventilation at 2、6、12 and 24 h post-treatment, and the control group was treated with a treatment regimen that alternated between high-flow oxygen therapy and noninvasive ventilation for 6 h. The partial pressure of arterial blood carbon dioxide (PaCO₂) and the level of decline, pH, oxygenation index, heart rate, respiratory rate, blood pressure, duration of noninvasive ventilation, dyspnea score, comfort score, diaphragm movement and 28-day survival rate were compared between the two groups.

There were no significant differences in baseline characteristics between the two groups, and the differences in PaCO₂, pH, PaO₂, oxygenation index, and heart rate, respiration rate, and blood pressure obtained at any of the study time points were not statistically significant (P>0.05). The duration of noninvasive ventilation in the intervention group was significantly lower than that in the control group over a 24 h period (4.53±8.10 vs. 12.00±0.00, P<0.001), and the intervention group had lower dyspnea scores and higher comfort scores (P=0.003, 0.010, respectively).

In the treatment of patients with AECOPD combined with type II respiratory failure, the modified respiratory support strategy not only effectively reduces PaCO₂, but also decreases the duration of noninvasive positive pressure ventilation, alleviates the symptoms of dyspnea, and improves patient comfort.

To investigate the effect of mild hypothermia therapy combined with intravenous thrombolysis in the treatment of patients with acute cerebral infarction (ACI) from pre-hospital.

From January 2022 to June 2023, Zhenjiang Emergency Center sent patients who were initially diagnosed as stroke to the hospital for treatment at the pre-hospital emergency site. Finally, 78 patients who were diagnosed as acute cerebral infarction were randomly divided into observation group (38 cases) and control group (40 cases). The patients in the control group received routine pre-hospital emergency measures, and the patients in the observation group began to implement mild hypothermia treatment before the hospital. The patients in the two groups were treated with alteplase intravenous thrombolysis after reaching the hospital. The National Institutes of Health Stroke Scale (NIHSS) score, activities of daily living scale (ADL), superoxide dismutase (SOD) and malondialdehyde (MDA) levels were compared between the two groups.

After 2 weeks of treatment, the NIHSS score, ADL score, SOD level and MDA level in the observation group were better than those in the control group, and the differences were statistically significant (all P<0.05).

Pre-hospital mild hypothermia therapy combined with intravenous thrombolysis significantly reduces the oxidative stress response and improves the prognosis for patients with acute cerebral infarction.

To explore the application values of scenario simulation teaching of case-based leaning (CBL) combined with improved mini-clinical evaluation exercise (Mini-CEX) in standardized training for emergency department residents.

A total of 41 residents participating in emergency standardized training at the Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School from August 2021 to July 2023 were selected as the research subjects. They were divided into an observation group (n=21) and a control group (n=20). The observation group received clinical training using scenario simulation based on CBL combined with improved Mini-CEX teaching method, while the control group received traditional teaching method. At the end of the training, theoretical test and three-station Mini-CEX assessment were conducted for both groups, and the satisfaction of the students was assessed using a questionnaire survey.

There was no statistically significant difference in theoretical scores between two groups (P>0.05), but the scores of three-station Mini-CEX assessment and teaching satisfaction in the observation group were significantly higher than those in the control group (P< 0.05).

Scenario simulation teaching based on CBL combined with improved Mini-CEX can significantly improve the comprehensive diagnosis and treatment level of emergency department residents in standardized training, enhance teaching quality, and increase residents' satisfaction. It is worth trying and promoting in emergency training bases.

To explore the regional differences of vulnerabilities in healthcare resources of primary healthcare institutions and their key influencing factors, providing evidence support for promoting the rational allocation and utilization of healthcare resources.

Based on the "pressure-carrying capacity" theory and expert consultation results, a vulnerability assessment model for healthcare resources in primary healthcare institutions was constructed. The vulnerability level was evaluated using the index method, and SPSS26.0 software was used to conduct vulnerability diagnosis and empirical analysis of relevant statistical data from various provinces in 2020.

The average comprehensive index of vulnerability of healthcare resources in primary healthcare institutions in 2020 was 1.152, with Guangxi (1.716), Xinjiang (1.711), and Qinghai (1.651) ranking in the top three. There were 7 provinces with safe vulnerability, 5 provinces with critical vulnerability, and 19 provinces with mild or above vulnerability. The t-test showed significant differences in 9 of the 15 indicators between the vulnerable group and the non-vulnerable group (P<0.05).

The healthcare resource system of primary healthcare institutions exhibits vulnerabilities under the dual effects of pressure and carrying capacity. These vulnerabilities are characterized by coupling amplification effects, shortage concentration effects, and universality.

To analyze the feasibility and effectiveness of recruiting first-aid volunteers in the training section of Kunshan First Aid Center to improve the translation of first-aid public welfare training results and to explore a sustainable management approach.

A total of 2023 volunteers from 2018 to 2018 were involved in this study and their information were collected. SPSS21 software was used to evaluate the general situation of volunteers, the results of the transformation, volunteer training management path and effectiveness with statistical and descriptive analysis.

The number of volunteers recruited and the number of volunteer services completed were increasing year by year, and the transformation rate of training results was high. The transformation forms were as follows: brochure, TV station, wechat public number, square social propaganda, net class training, and high social evaluation. In the survey results of volunteers accepting volunteer service, 59.79% of them supported the service throughout the year, 40.21% of them stopped service because of family (15.47%), work (19.59%) and personal reasons(5.15%). 35.05% of them wanted to learn first-aid knowledge, 28.87% had spiritual belief, and 19.59% followed the trend, 16.49% of them served the society under the influence of others. The evaluation of effect and the guarantee of training was the highlights in the management of the transformation of volunteer training results in the training section, which promoted the transformation of training results.

The training division selects first-aid volunteers as the target audience in the management of promoting the transformation of first-aid public welfare training results, and completes the transformation of training results in the three levels: trainees, working environment and organization in the management path. We should strengthen the management of idea and execution obstacle, pay attention to the preparation of transformation in the whole process of training, stimulate the transformation motivation, provide the transformation opportunity and then control the transformation result. Therefore, the management thought and goal are clear and the method is rigorous and operable, which is suitable for the management of the first-aid public welfare training activities

To comprehensively analyze the current epidemiological situation of dengue fever at the global level and in China, to assess the indigenous transmission risk of dengue fever in China in the coming period, and to propose recommendation on risk management.

The dengue epidemic and vector surveillance information of some countries and regions around the World and in China were described in general terms. The risk matrix method was used to assess the indigenous transmission risk caused by imported cases of dengue fever epidemic in different provinces of China.

In recent years, the global dengue epidemic had shown a trend of gradual increase, and the cumulative number of reported cases of dengue fever in the world in 2023 were more than 6.5 millions. The number of dengue fever cases reported in China from 2015 to 2023 showed a gradual increase. May to October was the epidemic season every year. Yunnan Province, Guangdong Province and Guangxi Zhuang Autonomous Region report a higher number of cases. At the present time, Mainland China faced a higher risk of importation than that of 2023, and the provinces with a high risk of importation of dengue fever triggering local epidemics were Guangdong Province and Yunnan Province.

It is recommended to pay continuous attention to the international epidemic situation, carry out timely tracking and management of imported cases, and implement sustainable mosquito vector surveillance measures.

To compare and analyze the framework and characteristics of health emergency management system in different countries, so as to provide reference for the governance direction of global health emergency management system.

Focusing on the current situation of the health emergency management system in various countries, the aim was to objectively analyze the shortcomings and deficiencies of the health emergency management system in various countries through research and comparison, and to extract suggestions for the direction of global health emergency management system governance.

Countries were similar in health authorities and their functions, disease control agencies and their functions, and public health emergency agencies and their functions. The United States showed a ows ar in health authorities and their functionsand a high degree of decentralization in horizontal management functions"; the United Kingdom adopted a opts ted Kingdom authorities and their functionsand a high degree of deemphasized diversified coordination under localized management.

Different countries have different characteristics of health emergency management systems, focusing on the governance direction of health emergency management systems, countries at different levels, such as the central and local vertical management, horizontal management of parallel departments at the same level, which should strengthen the linkage, effectiveness and operability of health emergency management, strengthen the legal support, improve the management system, and smooth operation mechanism.