To investigate the effect of integrated emergency nursing process on the rescue effect of patients with acute myocardial infarction (AMI).

Ninety AMI patients admitted to Xi'an International Medical Center Hospital from August 2023 to October 2024 were selected as the research subjects, including 48 males and 42 females; The age ranged from 41 to 70 years, with an average of (60.28±7.63) years. According to the random number method, they were divided into an observation group and a control group, with 45 cases in each group. The control group received routine emergency care procedures, while the observation group received integrated medical and nursing emergency care procedures. The time nodes related to emergency treatment, including onset to balloon dilation, first medical contact to balloon dilation, hospital gate to balloon dilation, and onset to hospital gate, pre- and post-emergency cardiac function indicators, including left ventricular ejection fraction (LVEF) and left ventricular end diastolic diameter (LVEDD), major adverse cardiovascular events (MACE) during hospitalization, and nursing satisfaction were compared between two groups of patients.

The time of onset-to-ballooning, first medical contact-to-ballooning, hospital gate-to-ballooning and onset-to-hospital gate in the observation group was shorter than that in the control group (P<0.05). Compared with the same group before first-aid, LVEF was significantly increased and LVEDD was significantly decreased in both groups after first-aid (P<0.05). After first-aid, LVEF in the observation group was significantly higher than that in the control group, and LVEDD was significantly lower in the control group (P<0.05). The incidence of major adverse cardiovascular events (MACE) during hospitalization in the observation group was lower than in the control group, and the nursing satisfaction was higher than the control group (P<0.05).

Integrated emergency nursing is helpful to improve the prognosis of AMI patients, shorten the emergency process, promote the recovery of cardiac function, reduce the incidence of MACE, and improve nursing satisfaction.

To explore the preventive effect of four-step rehabilitation program combined with motivational interview on acute attack after discharge in elderly patients with heart failure.

A prospective study was conducted on 126 elderly patients with HF admitted to the First Affiliated Hospital of Shihezi University from March 2023 to July 2024. They were divided into the control group and the study group according to the random number table method, with 63 cases in each group. The control group received routine rehabilitation guidance on the basis of routine management, and the study group received four-step rehabilitation program combined with motivational interview on the basis of routine management. Cardiac function [(Left ventricular ejection fraction (LVEF), cardiac output (CO), stroke volume (SV), 6-min walking distance (6MWD)], Chinese version of Heart Failure Self-care Scale, compliance score, Minnesota Heart Failure Quality of Life Questionnaire (MLHFQ) were compared between the two groups before intervention, at discharge and 3 months after discharge, and the acute attacks within 6 months after discharge were compared between the two groups.

Before intervention, there were no differences in cardiac function, Chinese version of Heart Failure Self-care Scale, compliance score and MLHFQ score between the two groups (P>0.05). At discharge and 3 months after discharge, the LVEF, CO, SV, 6MWD, SCHFI score and compliance score of the study group were higher or greater than those of the control group, and the MLHFQ score was lower than that of the control group (P<0.05). At the last follow-up, the acute attack rate of the study group was lower than that of the control group (P<0.05).

Four-step rehabilitation program combined with motivational interview can significantly improve the cardiac function of elderly HF patients and reduce the number of acute attacks after discharge.

To compare the effects of different emergency nursing methods in endoscopic treatment of patients with acute upper gastrointestinal bleeding.

A total of100 patients with acute upper gastrointestinal bleeding admitted to the Fifth Hospital of Huangshi City from January 2022 to December 2024 were selected; there were 55 males and 45 females, the age ranged from 27 to 65 years old, with an average of (46.03±10.23) years. They were randomly divided into an observation group and a control group, with 50 patients in each group, using a random number table. The control group received routine perioperative care, while the observation group received perioperative dual track emergency care, both of which continued until the patient was discharged. The hemostatic outcomes (immediate hemostasis success, rebleeding within 72 hours, and conversion to surgical intervention) were compared between the two groups, and the changes in self-rating depression scale (SDS), self-rating anxiety scale (SAS), hemoglobin (Hb), albumin (ALB), and prealbumin (PA) before endoscopic treatment and discharge, as well as the length of hospital stay, hospitalization costs, and nursing satisfaction were compared.

The observation group had a rebleeding rate within 72 hours of 2.00%, which was lower than the control group's 14.00% (P<0.05). At discharge, the SDS and SAS scores of the observation group were (36.04±3.51) points and (37.46±4.02) points, both of which were lower than those of the control group (40.27±3.92) points and (41.85±4.15) points (P<0.05). At discharge, the Hb, ALB, and PA levels in the observation group were (128.32±15.23) g/L, (40.11±3.52) g/L, and (225.69±15.32) mg/L, all higher than those in the control group (121.57±11.05) g/L, (36.87±3.20) g/L, and (213.25±13.07) mg/L (P<0.05). The hospitalization time and hospitalization expenses of the observation group were (6.35±1.83) days and (0.86±0.09) yuan, both of which were shorter/less than those of the control group (7.60±1.24) days and (0.92±0.13) yuan (P<0.05). The overall satisfactory rate of the observation group with nursing care was 94.00%, which was higher than the control group's 78.00% (P<0.05).

Perioperative dual track emergency nursing can help reduce the rebleeding rate of patients with acute upper gastrointestinal bleeding undergoing endoscopic treatment, alleviate negative emotions, and improve nutritional status. It is worthy of clinical promotion.

To analyze the infection status and preventive measures of multidrug resistant organism (MDRO) in patients with oral and maxillofacial trauma.

A retrospective analysis was conducted on the medical records of 71 hospitalized MDRO patients with oral and maxillofacial trauma received by Huangshi Hospital of Traditional Chinese Medicine from January 2023 to February 2025, including 41 males and 30 females, the age ranged from 22 to 71 years, with an average of (53.01±7.95) years. During the same period, 78 patients with oral and maxillofacial trauma admitted to our hospital who were hospitalized but did not have MDRO infection were selected as the control group, including 37 males and 41 females, the age ranged from 20 to 73 years, with an average of (55.30±8.42) years. The distribution and drug resistance of pathogenic bacteria in MDRO infected patients were detected, and the distribution of infection sites was analyzed., and the risk factors of MDRO infection in patients with oral and maxillofacial trauma were analyzed by univariate and multivariate logistic regression analysis.

A total of 78 strains of MDRO were detected in 71 patients with oral and maxillofacial trauma, mainly Escherichia coli, MRSA and Klebsiella pneumoniae. The resistance of Escherichia coli and Klebsiella pneumoniae to cephalosporins, quinolones and sulfonamides was high, and the resistance of methiclococcus aureus to penicillins, macrolides and lincoamides was high. Univariate analysis showed that the rates of open injury, use of antibiotics ≥3 kinds, use of antibiotics ≥7 days, stay ≥10 days in MDRO patients hospitalized with oral and maxillofacial trauma were higher than those in the control group (P<0.05). Multivariate logistic regression analysis showed that open injury, use of antibiotics ≥3 kinds, use of antibiotics ≥7 d, and hospital stay ≥10 d were the risk factors for oral and maxillofacial trauma inpatient MDRO infection (P<0.05).

The MDRO in patients with oral and maxillofacial trauma is mainly composed of gram-negative bacteria, which is mostly associated with wound and lower respiratory tract infection, and is related to multiple risk factors. Clinical preventive countermeasures should be strengthened.

To compare the effects of intravascular ultrasound (IUVS) and optical coherence tomography (OCT) guided emergency percutaneous coronary intervention (PCI) on acute myocardial infarction.

A total of 80 patients with acute myocardial infarction admitted to our hospital from May 2023 to November 2024 were divided into IUVS group and OCT group, with 40 cases in each group; there were 47 males and 33 females, the age ranged from 51 to 73 years, with an average of (63.51±6.59) years. Emergency PCI under IVUS guidance was performed in the IVUS group, while emergency PCI under OCT guidance was performed in the OCT group. The preoperative characteristics of lesions (plaque rupture, plaque erosion, lipid and fibrous plaques, and calcified nodules), preoperative coronary conditions [minimum lumen area (MLA), reference vessel diameter, minimum lumen diameter, lesion length, and bifurcation lesion], perioperative situation (number of stent placement, intraoperative dilation times, minimum stent area after stent placement, stent placement success rate, and length of hospital stay), detection rate of immediate stent implantation defects after PCI (stent mal-expansion, poor adhesion, immediate thrombosis, marginal dissection, and tissue prolapse), the incidence of major adverse cardiovascular events (MACE) 30 days after surgery (angina pectoris, recurrent myocardial infarction, and malignant arrhythmias) were compared between the two groups.

The plaque rupture and plaque erosion in OCT group were higher than that in the IVUS group (P<0.05); the MLA, reference vessel diameter, minimum lumen diameter, lesion length and bifurcation lesion were compared between the two groups, with statistically significant (P>0.05); the intraoperative dilation times in OCT group were more than that in IVUS group, and the hospital stay was shorter than that in IVUS group (P<0.05); the total detection rate of stent implantation defects immediately after PCI in OCT group was higher than that in IVUS group (P<0.05); there was no statistical significance in the total incidence of 30dMACE between the two groups (P>0.05).

Compared with IVUS, OCT-guided emergency PCI is better in the treatment of patients with acute myocardial infarction, which can effectively identify the nature of preoperative lesions and improve the detection rate of poor stents, shorten hospital stay, and is worthy of clinical promotion.

To investigate the therapeutic value and safety profile of combined nebulized budesonide and salbutamol for pediatric acute severe asthma exacerbations.

This prospective, randomized and controlled trial enrolled 94 children with acute severe asthma exacerbations treated between January 2020 and December 2024. Patients were randomly assigned to a combination therapy group (n=48, budesonide + salbutamol nebulization)and a monotherapy group (n=46, salbutamol nebulization alone). Comparative assessments included clinical efficacy evaluation, pulmonary function parameters, inflammatory biomarker modulation, symptom resolution rates, medication safety, and subsequent recurrence frequency.

The combination therapy group demonstrated significant advantages, including higher total effective rate (P<0.05), superior pulmonary function recovery, with greater improvements in FEV1, PEF, and FEV1/FVC compared to the monotherapy group (P<0.05), more pronounced reduction in inflammatory markers (IL-6, TNF-α, hs-CRP) (P<0.05), accelerated symptom resolution (wheezing, dyspnea, coughing) and shortened hospitalization duration (P<0.05), comparable adverse reaction rates (P>0.05) and significantly reduced three-month recurrence risk (P<0.05).

For children with acute severe asthma, combined budesonide-salbutamol nebulization speeds symptom relief, aids lung function recovery, reduces airway inflammation, lowers recurrence risk, and it is safe, warranting clinical promotion. This regimen offers integrated benefits and is a valuable clinical option.

To explore the role of forsythoside A (FA) in regulating neutrophil extracellular traps (NETs) and alleviating sepsis-related ARDS, as well as its possible mechanism.

A total of 80 mice were randomly divided into sham, model (CLP), FA, and FA+PPAR-γ groups. A sepsis-induced lung injury mice model was established using the classic cecal ligation and puncture (CLP) procedure. The sham group underwent only laparotomy. siPPAR-γ (10 nmol/20g) was administered via tail vein injection (twice a week for 2 weeks), while FA was administered via intraperitoneal injection (80 mg/kg, once daily for 3 days). After successful model establishment, Kaplan-Meier survival curves were used to analyze the cumulative 7-day survival rate of 10 mice per group. For the remaining mice, six per group were randomly selected to collect lung tissue. Inflammatory factors (TNF-α, IL-6, IL-1β) and NET markers (NE-DNA, MPO-NDA) were detected using ELISA kits. SOD, MDA, and ROS levels were measured by spectrophotometry. The lung wet/dry weight (W/D) ratio was calculated. Pathological changes were observed under light microscope after H&E staining, and lung injury histopathological scoring was conducted. Immunofluorescence was used to detect H3-cit protein expression in lung tissue. Western blotting was performed to measure the relative expression levels of PPAR-γ, H3-cit, MPO, and NE proteins.

Kaplan-Meier survival curve analysis revealed that the 7-day cumulative survival rate in the FA group was significantly higher than in the CLP and FA+PPAR-γ groups (P<0.05). The CLP group showed partial alveolar destruction, thickened alveolar septa, extensive inflammatory cell infiltration, alveolar and partial alveolar hyaline membrane formation, and alveolar collapse. In the FA group, H&E staining showed significant reduction in inflammatory cell infiltration, thinner alveolar septa, and less alveolar collapse. Compared to the sham group, the CLP group exhibited higher lung injury histopathological scores and W/D ratios (P<0.05), increased levels of inflammation factors (TNF-α, IL-6, IL-1β, P<0.05), elevated NE-DNA and MPO-NDA expressions (P<0.05), increased MDA and ROS levels (P<0.05), and decreased SOD levels (P<0.05). PPAR-γ protein expression was reduced (P<0.05), while H3-cit, MPO, and NE protein expressions were elevated (P<0.05). Compared to the CLP group, the FA group showed lower lung injury histopathological scores and W/D ratios (P<0.05), decreased levels of inflammatory factors (TNF-α, IL-6, IL-1β, P<0.05), reduced NE-DNA and MPO-NDA expression (P<0.05), lower MDA and ROS levels (P<0.05), higher SOD levels (P<0.05), and increased PPAR-γ protein expression (P<0.05). H3-cit, MPO, and NE proteins were reduced (P<0.05).

Forsythoside A alleviates sepsis-related ARDS by activating PPAR-γ to inhibit the formation of neutrophil extracellular traps.

To investigate the diagnostic value of scrotal ultrasonography, testicular ischemia and suspicious torsion score (TWIST) system and peripheral blood platelet volume (MPV) in testicular torsion in children.

A retrospective analysis was performed on the case data of 150 children admitted to hospital due to pain and swelling of the scrotum from August 2020 to December 2024, according to the results of testicular exploration, 92 cases were in the testicular torsion group and 58 cases in the non-testicular torsion group. The diagnostic results of scrotal color Doppler ultrasound examination and testicular exploration were compared, the color ultrasound examination of scrotum, score of TWIST system at admission and peripheral blood MPV levels at the morning after admission were compared between the two groups. The multivariate logistic regression analysis was used to analyze the risk factors of testicular torsion in children, and the receiver operating curve (ROC) to analyze the diagnostic value of scrotal ultrasonography, TWIST score and MPV alone and in combination.

The kappa consistency test between scrotal color Doppler ultrasound examination and testicular exploration was statistically significant (P<0.05). The testis volume, testicular bleeding grading (Arda grade) and TWIST system score were statistically significant differences between the two groups (P<0.05); the peripheral blood MPV levels in testicular torsion group was higher than that in the non-testicular torsion group (P<0.05). The multivariate logistic regression analysis showed that testicular volume, Arda grade, TWIST score and MPV were all risk factors for children with testicular torsion (P<0.05). ROC analysis showed that combined detection of testicular volume, Arda grade, TWIST score and MPV had higher diagnostic value for children with testicular torsion than single detection (P<0.05).

Scrotal color Doppler ultrasound has certain value in the diagnosis of testicular torsion. Combined with TWIST system score and MPV detection, it can further improve the diagnostic effect of testicular torsion in children.

To understand the first-aid knowledge, attitude and behavior level of employees in township enterprises, as well as the safety management status of enterprises, aimed to provide guidance for improving the health emergency response ability of enterprises.

From June to December 2024, the convenient sampling method was used to select employees of township enterprises in Kunshan City as the research object. The first-aid knowledge, attitude and behavior questionnaires were used for investigation; the persons in charge of enterprise safety management were Interviewed and a questionnaire was made based on the type of emergency equipment in the operating environment, quantity, usage, and the willingness of employees to receive first aid knowledge training.

A total of 3,388 employees participated in the pre-hospital first aid knowledge questionnaire, with a first-aid knowledge score of (15.23±2.14), a first-aid attitude score of (38.45±5.67), and a first-aid behavior score of (28.20±4.95); Different training experiences had statistical significance for the differences in first-aid knowledge and behavior scores. The P values were 0.001 and 0.002, respectively. There was no statistical significance for the difference in first-aid attitude score, with a (P>0.05); Questionnaires on the safety management status of 39 enterprises were prepared. Enterprises set up 100% of security personnel, and 58.97% of security personnel received first-aid training. The proportion of AED for first-aid equipment in enterprises was 25.64%, and the AED training rate of enterprise employees was 90.00%.

The first-aid knowledge of employees in township enterprises is at a medium and low level, and their first-aid attitude and behavior are at a medium level. The number and type of first-aid equipment configured by enterprises and the training of employees on the use of first aid equipment are insufficient. Safety management positions meet the requirements of fixed personnel, fixed number, fixed post, fixed responsibility and regular training. It is necessary for enterprises to strengthen the transformation of safety personnel training achievements and formulate reasonable first-aid training and drills for all personnel to improve their ability to cope with accidental injuries.

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To explore the establishment and validation of a risk prediction model for acute radiation dermatitis (ARD) after breast-conserving surgery for breast cancer.

A total of 123 patients who received radiotherapy after breast-conserving surgery for breast cancer in our hospital from January 2020 to October 24 were selected as the study subjects, and were included in the training set (n=86) and the validation set (n=37) according to the ratio of 7:3. According to whether patients in the training set have developed ARD, they were divided into the ARD group and the non ARD group. The occurrence of ARD in patients was recorded, and multivariate logistic regression analysis was conducted to identify risk factors for ARD, to construct a predictive model, and to validate the value of the model in clinical applications using ROC curves.

Of the 86 patients who received radiotherapy after breast-conserving surgery for breast cancer, 67 patients developed ARD (77.91%). By univariate analysis, there was no significant difference between ARD group and non ARD group in body mass index, smoking history, drinking history, hypertension, coronary heart disease, pathological type, TNM stage, triple negative breast cancer, HER2, ER and PR (P>0.05). The age in ARD group was significantly lower than that in non ARD group (42.31±7.67 vs 56.27±9.98, P<0.001); The ARD group combined with diabetes was significantly higher non ARD (34.33% vs 10.53%, P<0.05); The ARD group proportion of malnutrition was significantly higher non ARD group (43.28% vs 10.53%, P<0.01); The ARD group radiation dose was significantly higher non ARD group (57.82±3.24 vs 48.97±4.35, P<0.001). Multivariate logistic regression analysis showed that age, nutritional status, combined diabetes, radiotherapy dose entered the regression model (P<0.05), which were independent risk factors for the occurrence of radiation-induced ARD. A prediction model of radiation-induced ARD was established: P=-2.22-2.35×age+1.75×nutritional status+2.68×combined diabetes+1.99×radiation dose. The ROC curve was used to validate the predictive value of the above model for ARD occurrence. The results showed that the area under the curve was 0.876 (P=0.000, 95%CI0.828-0.924), with a sensitivity of 89.90% and a specificity of 71.00%.

Age, nutritional status, combined diabetes, radiation dose are important factors that affect the occurrence of ARD caused by radiotherapy after breast-conserving surgery for breast cancer. According to the above factors, the corresponding risk prediction model is developed, and the prediction effect of the model is good, which is worth further analysis.