To investigate clinical features and characteristics of coronary artery lesions of Han, Uygur and Khalkhas patients with acute myocardial infarction (AMI) in Kizilsu Kirgiz Autonomous Prefecture of Xinjiang Uygur Autonomous Region.

A retrospective study was conducted among the patients diagnosed with AMI and performed coronary angiography between January 2017 and January 2019 in Kizilsu Kirgiz Autonomous Prefecture People’s Hospital. There were 150 males and 42 females, aged from 30 to 89 years, with an average age of (61.99±12.07) years old. According to different ethnic groups, the patients were divided into Han group (40 cases), Uygur group (100 cases) and Kirgiz group (52 cases). Male patients were divided into Han male group (28 cases), Uyghur male group (78 cases) and Kirgiz male group (44 cases); according to different ages, the patients were divided into the youth group (age ≤ 44 years old, 14 cases) and the non-youth group (age>44 years old, 178 cases); according to the outcome of the disease, the patients were divided into the survival group (167 cases) and the death group (25 cases). The clinical characteristics of Han, Uygur and Kirgiz, including body mass index (BMI), drinking history, arterial blood pressure, white blood cell count (WBC), red blood cell count (RBC), hemoglobin (Hb), platelet count (PLT), cardiac troponin T (cTnT), homocysteine (Hcy), and type B brain natriuretic peptide (BNP), were analyzed. The distribution of diseased vessels, the distribution of criminal blood vessels, the distribution of coronary lesions and Gensini score between groups were compared.

A total of 192 patients with AMI were enrolled, including 40 cases of Han, 100 cases of Uygur, and 52 cases of kirgiz. The body mass index(BMI) levels of the two minority groups were higher than that of Han group(P<0.05); the drinking rates of the two minority groups were higher than that of Han group(P<0.017); the counts of red blood cells (RBC) and platelets(PLT), the levels of cardiac troponin T(cTnT) were higher in the two minority groups than that in Han group(P<0.05). Blood pressure in Kirgiz group was higher than that in Uygur group and Han group (P<0.05). The count of white blood cells (WBC) in Uygur group was higher than that in Han group(P<0.05); the level of homocysteine(Hcy) in Uygur group was higher than that in Kirgiz and Han groups (P<0.05); the level of B-type natriuretic peptide(BNP) in Kirgiz group was higher than that in Han group(P<0.05). The proportion of three-vessel disease in Uygur and Han groups was higher than that in Kirgiz group(P<0.05) and the proportion of single-vessel disease in Kirgiz group was higher than that in Uygur and Han groups(P<0.05); the single-vessel disease was the most common in the youth group, and the proportion of single-vessel disease was higher than that in the non-youth group(P<0.05); the three-vessel disease was the most common in the non-youth group, which had a higher proportion of three-vessel disease than the young group (P<0.05); the Gensini scores of patients in Uygur and Han group were higher than that in Kirgiz group(P<0.05); the Gensini score in the survival group was lower than that in the death group(P<0.05).

There are ethnic differences in clinical features and coronary lesions among AMI patients in Kizilsu Kirgiz Autonomous Prefecture of Xinjiang Uygur Autonomous Region. The incidence of three-vessel disease in Uygur and Han patients with AMI is higher than that of Kirgiz and the severity of coronary artery lesions is heavier than that of Kirgiz. In clinical practice, targeted individualized prevention and treatment measures should be taken for AMI patients of different races.