Clinical efficacy ofinterventional therapy of acute massive pulmonary embolism

doi:10.3877/cma.j.issn.2095-9133.2020.02.007

Abstract

Abstract:

Objective

To investigate the safety and efficacy of interventional therapy of acute massive pulmonary embolism.

Methods

Clinical data of 49 patients with acute massive pulmonary embolism who were treated in Provincial Hospital affiliated to Shandong First Medical University and Jinan Municipal Hospital of Traditional Chinese Medicine form October 2014 to June 2018 were analyzed retrospectively. Among them, 32 were male and 17 were female, the age was 22 to 55 years, and the mean age was (36±8.18) years. All patients with acute massive pulmonary embolism were treated with inferior vena cava filter implantation, pulmonary artery catheter directed thrombolysis, mechanical thrombus breakage, catheter thrombus suction and so on, and the effect of interventional therapy of acute massive pulmonary embolism was evaluated by observing the improvement of the patients’ clinical symptoms and comparing pre- and post-operative pulmonary hypertension and Miller score.

Results

In 47 patients (47/49, 95.92%), the symptoms of dyspnea, chest tightness, chest pain, cough and hemoptysis were improved, and pulmonary artery pressure, oxygen saturation, partial pressure of oxygen and Miller score were significantly increased (P<0.05). Two patients (2/49, 4.08%) showed no significant improvement in symptoms.

Conclusion

The interventional therapy of acute massive pulmonary embolism could recover the pulmonary perfusion flow with significant effect.

Key words: Thrombolytic therapy, Acute massive pulmonary embolism, Pulmonary artery angiography, Interventional therapy

Yutao Wang, Kuiquan Song, Youwen Zhang, Yan Sun. Clinical efficacy ofinterventional therapy of acute massive pulmonary embolism[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2020, 06(02): 92-97.

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Figures/Tables 7

References 19

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项目		统计
伴随症状(例)		?
?	呼吸困难	49
?	胸痛	49
?	咯血	11
肺动脉压(mm Hg)		43±4.83
发病因素(例)		?
?	骨折	16
?	外科术后	12
?	剖宫产术后	10
?	无明显诱因	11
肺栓塞发生部位(例)		?
?	肺动脉主干	5
?	右肺动脉	16
?	左肺动脉	17
?	双肺动脉	11
发病至接受治疗时间(h)		45.67±22.52

项目		统计
伴随症状(例)		?
?	呼吸困难	49
?	胸痛	49
?	咯血	11
肺动脉压(mm Hg)		43±4.83
发病因素(例)		?
?	骨折	16
?	外科术后	12
?	剖宫产术后	10
?	无明显诱因	11
肺栓塞发生部位(例)		?
?	肺动脉主干	5
?	右肺动脉	16
?	左肺动脉	17
?	双肺动脉	11
发病至接受治疗时间(h)		45.67±22.52

分组	肺动脉压(mmHg)	Miller评分
治疗前	31.5±4.9	22.1±5.4
治疗后	22.9±4.1	12.3±4.3
t值	10.21	10.67
P值	<0.05	<0.05

分组	肺动脉压(mmHg)	Miller评分
治疗前	31.5±4.9	22.1±5.4
治疗后	22.9±4.1	12.3±4.3
t值	10.21	10.67
P值	<0.05	<0.05

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