Abstract:
Objective To investigate the risk factors of deep vein thrombosis (DVT) in burn patients.
Methods The burn patients with DVT in recent 3 years were collected as the observation group, and the patients without DVT in the same period were selected as the control group. The platelet count, D-dimer, hematocrit, prothrombin time, fibrinogen, whole blood viscosity, P-selectin and anticardiolipin antibody were detected and analyzed. The data of gender, age, body weight, burn area, third degree burn area, D-dimer; bed time after injury, times of deep vein catheterization, and days of deep vein catheterization were collected and analyzed by logistic regression.
Results There were no significant differences in age, gender and burn area between the control group and the observation group (P>0.05). Compared with the control group, the platelet count of the observation group was (525.1±144.8) vs. (402.6±144.6), P<0.05; the D-dimer of the observation group and the control group was(1.71±0.83) vs. (0.95±0.55), P<0.01; the P-selectin content in the observation group was (389.1±68.3) vs. (294.3±61.5), P<0.01, with statistical significance. Logistic regression analysis showed that D-dimer (B=1.725, OR=5.612, P<0.05) may be a risk factor for DVT in burn patients.
Conclusions Abnormal increase of platelets and P-selectin may be important indicators of prethrombotic state. D-dimer is an independent risk factor for DVT in burn patients.
Key words:
Burn,
Deep vein thrombosis,
D-dimer,
P-selectin
Quan Li, Te Ba, Lingfeng Wang, Sheng Jun Cao, Biao Zhou, Zengqiang Yan, Qiang Chen, Zhihui Hou. Risk factors of deep venous thrombosis in burn patients[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2021, 07(01): 30-33.