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Chinese Journal of Hygiene Rescue(Electronic Edition) ›› 2018, Vol. 04 ›› Issue (03): 157-161. doi: 10.3877/cma.j.issn.2095-9133.2018.03.007

Special Issue:

• Original Article • Previous Articles     Next Articles

Comparison between conventional coagulation testing and thromboelastography for evaluation of trauma-induced coagulopathy in abdominal trauma patients

Yifu Zhou1, Zhenguo Zhao1, Shuanghai Liu1,()   

  1. 1. Department of general surgery, Jiangyin people’s Hospital Affiliated to Medical College of Southeast University, Jiangyin 214400, China
  • Received:2018-05-02 Online:2018-06-18 Published:2018-06-18
  • Contact: Shuanghai Liu
  • About author:
    Corresponding author: Liu Shuanghai, Email:

Abstract:

Objective

To compare the clinical usage of TEG (thromboelastography, TEG) and (conventional coagulation tests, CCT) in diagnosing trauma-induced coagulopathy.

Methods

The clinical data of 38 patients with abdominal trauma, from January 2017 to January 2018, were prospectively reviewed. Both of thromboelastography(TEG) and CCT were immediately performed at the patients’ arrival. Data were analyzed to compare the differences of sensitivity of the two test methods in finding TIC of all trauma patients and only in the patients who got hurt within 6 hours, and the correlation of two methods with the ISS. All data were analyzed by using chi-square test, t-test, Fisher exact test and Spearman rank analysis.

Results

The CCT results of 8 (21.1%) patients were positive, and the TEG results of 21 (55.2%) patients were positive. Furthermore, there was 1 patient showing negative in the TEG among the 8 patients whose CCT results were positive, while 14 patients showing negative in the CCT among the 21 patients whose TEG results were positive. The significant difference between the two groups (P =0.037) can be noticed. There were 13 patients admitted to hospital within 6 hours, among whom 3 (23.1%) patients were positive in CCT and 9 (69.2%) patients were positive in TEG. All the 3 patients with positive CCT results were also positive in TEG, and the 6 patients with positive TEG results were negative in CCT. There was significant difference between the two different groups (P =0.028) as well. R value in TEG test was related to ISS, and PT, APTT, K value were not related to ISS.

Conclusion

Based on our preliminary results, TEG was better than CCT in diagnosing TIC (trauma-induced coagulopathy)and ATC (Acute Traumatic Coagulopathy), with higher positive rates and better sensitivity.

Key words: Trauma-Induced Coagulopathy(TIC), Conventional Coagulation Testing(CCT), thrombelastogram(TEG), injury severity score(ISS)

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