To analyze the clinical characteristics profile of Han, Uygur and Khalkhas patients with acute myocardial infarction (AMI) and assess the risk factors affecting the mortality of patients in Kizilsu Kirgiz Autonomous Prefecture of Xinjiang Uygur Autonomous Region.

A retrospective study was conducted among the patients diagnosed with AMI between January 2016 and November 2017 in the cardiovascular medicine department of Kizilsu Kirgiz Autonomous Prefecture People’s Hospital and performed coronary angiography. Data on demographic characteristics, ethnic groups, underlying diseases, blood and biochemical indices, coronary angiographic results and clinical outcome were collected. The differences of clinical characteristics among the AMI patients of the three ethnic groups were compared. According to the clinical outcome, the patients were divided into survivor and non-survivor groups. The risk factors affecting the mortality of patients of the three ethnic groups were identified by Logistic regression analysis. All statistical description and analysis was conducted by SPSS 22.0.

175 AMI patients were collected, of which the number of Han patients was 41, the number of Khalkhas patients was 47 and the number of Uygur patients was 87. 25 patients were dead finally. The mortality rate of Han, Khalkhas and Uygur patients was 12.19%, 17.02% and 13.79%, respectively. There was no statistical significance among the mortality rates of three ethnic groups. The drinking rate of ethnic minorities AMI patients was higher than that of Han group. The difference was statistically significant (P<0.05). As the same, the systolic blood pressure (SBP) levels (P<0.05), diastolic blood pressure (DBP) levels (P<0.05), white blood cell (WBC) count (P<0.001), neutrophilic granulocyte (NE)% (P<0.05) and serum cardiac troponin T (cTNT) levels (P<0.001) of ethnic minority patients were higher than that of Han group. But the hemoglobin (HB) levels of ethnic minority patients was lower than that of Han group (P<0.05). 56.10 % of Han AMI patients had combined with multi-vessel coronary artery infarction and the proportion was higher than that of ethnic minority patients (P<0.05). In Logistic regression analysis, the risk factors affecting mortality were the plasma fibrinogen (FIB) levels (P<0.05), red blood cell (RBC) count (P<0.05) and multi-vessel coronary artery infarction (P<0.05).

There were differences in drinking rate and increased levels of blood pressure, WBC, NE%, HB, cTNT and the number of vessels in coronary artery infarction at the time of AMI between ethnic minority groups and Han group in Kizilsu Kirgiz Autonomous Prefecture of Xinjiang Uygur Autonomous Region. The plasma FIB levels, RBC count and multi-vessel coronary artery infarction were the important risk factors responsible for mortality of AMI in three ethnic groups.