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Chinese Journal of Hygiene Rescue(Electronic Edition) ›› 2023, Vol. 09 ›› Issue (04): 209-214. doi: 10.3877/cma.j.issn.2095-9133.2023.04.004

• Original Article • Previous Articles    

Analgesic effect of propofol and dexmedetomidine on interhospital transport in patients with tracheal intubation

Xin Pan, Jiangtao Yin, Chao Wang, Hui Gu, Wei Chen, Zhiwei Sun, Xin Wang, Jinhui Zhang()   

  1. Department of Emergency, Zhenjiang Emergency Center, Zhenjiang 212003, China
    Department of ICU, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China
  • Received:2023-07-20 Online:2023-08-18 Published:2024-01-22
  • Contact: Jinhui Zhang

Abstract:

Objective

To compare the sedative effect of traditional sedative propofol and dexmedetomidine (Dex) in interhospital transport of tracheal intubation patients.

Methods

A total of 82 patients with tracheal intubation who were transported from the Affiliated Hospital of Jiangsu University to outside Zhenjiang City by Zhenjiang Emergency Center from June 2021 to June 2023 were retrospectively observed. They were divided into propofol group and Dex group according to the sedative drugs used in the transport process. Hematologic indexes, APACHEⅡ score, SOFA score, incidence of adverse events during transport, transport cause, transport distance, transport time, tracheal intubation time after transfer, ICU stay and total hospital stay and 28-day mortality were compared within 24 hours before and after transport.

Results

There was no significant difference between propofol group and Dex group in gender, age, underlying diseases and transport etiology (P>0.05). The APACHEⅡ score of patients in propofol group after transport was significantly higher than that before transport (P<0.05), and the incidence of total adverse time during transport was significantly higher in propofol group than that in dexmetropil group, with statistical significance (P<0.05). After transport, tracheal intubation time and total hospital stay in Dex group had no statistical significance compared with propofol group (P>0.05), but ICU stay time and 28-day mortality were significantly lower than those in propofol group, with statistical significance (P<0.05).

Conclusion

Dex can improve the safety of interhospital transport in patients with tracheal intubation, improve prognosis and reduce medical burden.

Key words: Interhospital transport, Propofol, Dexmedetomidine, Tracheal intubation

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