Abstract:
Objective
To analyze the impact of early mechanical ventilation on the mortality of adult in-hospital cardiac arrest （IHCA） retrospectively and to provide a theoretical basis for whether early mechanical ventilation should be implemented in IHCA patients.
Methods
This study included 1540 adult IHCA patients who received at least two minutes of external chest compressions at National Taiwan University Hospital from 2006 to 2014. Mortality of IHCA patients was the outcome indicator used， and the relationship between early mechanical ventilation and mortality was analyzed using univariate analysis and multivariate logistic regression models.
Results
Among the 1540 adult IHCA patients， 329 （21.36%）received early mechanical ventilation， while 1211 （78.64%） did not. The respective mortality rates were 89.67% （95% CI： 86.38～92.96） and 84.39% （95% CI： 82.35～86.44）. The multivariate logistic regression model showed that the risk of death for IHCA patients receiving early mechanical ventilation was increased by 58% （OR： 1.580， 95% CI： 1.03～2.43， P=0.04） compared to those who did not receive mechanical ventilation.
Conclusion
Early mechanical ventilation is an independent risk factor of mortality in IHCA patients，and it may increase the death rate in these patients.
Key words:
In-hospital cardiac arrest,
Early mechanical ventilation,
Mortality,
Cardiopulmonary resuscitation
Qingwen Liu, Yong Han, Lidan Chen, Zhe Deng. Impact of early mechanical ventilation on mortality rates in adult in-hospital cardiac arrest: a retrospective cohort study[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2024, 10(04): 203-206.