To design surgical risk assessment system to systematically analyze the risk of developing post-operative sepsis and death of HIV-infected patients.

A retrospective study was conducted on clinical data of 764 HIV-infected patients admitted into Shanghai Public Health Clinical Center from January 2008 to December 2014. According the sepsis result, the patients were divided into two groups. The average score of the two groups were used to calculate the sensitivity and specificity value of the assessment system. Each of five indices including CD4 level, incision category, surgery grade, opportunistic infections and organ function were set for four grades, scoring from 1 to 4 points.

Post-operative sepsis occurred in 256 patients, with morbidity of 34% (256/764). Eleven patients were died of serious sepsis in 30 days after surgery, with mortality of 1.4%(11/764). The average score of surgery risk was 11.62 in sepsis group while 7.22 in non-sepsis group. The cutoff value was set 9.5, when the sensitivity and specificity was 95.1% and 89.8%, respectively.

The assessment system proposed in this study can predict the surgery risk of HIV-infected patients and can help surgeons take effective countermeasures.