Efficacy of ordinary heparin in the treatment of severe heat stroke combined with coagulation dysfunction

doi:10.3877/cma.j.issn.2095-9133.2017.06.011

Chinese Journal of Hygiene Rescue(Electronic Edition) ›› 2017, Vol. 03 ›› Issue (06): 365-366. doi: 10.3877/cma.j.issn.2095-9133.2017.06.011

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Efficacy of ordinary heparin in the treatment of severe heat stroke combined with coagulation dysfunction

Qihan Zheng¹, Xiaocheng Zhao¹(), Jin Xu¹

Received:2017-09-05 Online:2017-12-18 Published:2017-12-18
Contact: Xiaocheng Zhao

Abstract

Qihan Zheng, Xiaocheng Zhao, Jin Xu. Efficacy of ordinary heparin in the treatment of severe heat stroke combined with coagulation dysfunction[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2017, 03(06): 365-366.

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组别		PLT	APTT	PT	FIB
治疗组		?	?	?	?
?	治疗前	172.65±27.93	13.29±1.22	28.40±2.56	3.46±0.48
?	治疗24 h后	147.80±42.00	33.04±0.91	36.20±5.52	3.14±0.49
对照组		?	?	?	?
?	治疗前	186.20±23.28	14.86±0.73	23.40±1.71	1.85±0.20
?	治疗24 h后	63.60±19.09	13.28±0.88	36.04±0.95	5.97±0.62
t值		12.88	4.37	20.43	20.00
P值		<0.01	<0.01	<0.01	<0.01

组别		PLT	APTT	PT	FIB
治疗组		?	?	?	?
?	治疗前	172.65±27.93	13.29±1.22	28.40±2.56	3.46±0.48
?	治疗24 h后	147.80±42.00	33.04±0.91	36.20±5.52	3.14±0.49
对照组		?	?	?	?
?	治疗前	186.20±23.28	14.86±0.73	23.40±1.71	1.85±0.20
?	治疗24 h后	63.60±19.09	13.28±0.88	36.04±0.95	5.97±0.62
t值		12.88	4.37	20.43	20.00
P值		<0.01	<0.01	<0.01	<0.01

组别	例数	治疗前APACHEⅡ	治疗24 h后APACHEⅡ	死亡率(%)
治疗组	20	20.90±1.68	16.85±5.74	25
对照组	10	21.00±1.41	19.90±5.69	30
t值	?	2.98	0.61	?
P值	?	<0.01	>0.05	?

组别	例数	治疗前APACHEⅡ	治疗24 h后APACHEⅡ	死亡率(%)
治疗组	20	20.90±1.68	16.85±5.74	25
对照组	10	21.00±1.41	19.90±5.69	30
t值	?	2.98	0.61	?
P值	?	<0.01	>0.05	?

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5	Roberts GT, Ghebeh H, Chishti MA, et al.Microvascular injury，thrombosis，inflammation，and apoptosis in the pathogenesis of heatstroke：a study in baboon model[J]．Arterioscler Thromb Vasc Biol，2008，28(6):1130-1136.

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