Application of mild hypothermia therapy in pre-hospital emergency treatment of stroke

doi:10.3877/cma.j.issn.2095-9133.2023.03.005

Abstract

Abstract:

Objective

To explore the application effect of mild hypothermia therapy before hospitalization on the protection of brain function in stroke patients.

Methods

From January 2022 to June 2022, Zhenjiang Emergency Center used the G-FAST scoring method to evaluate the patients at the pre-hospital emergency scene, and send the patients initially judged as stroke to the hospital for treatment. 85 patients were finally diagnosed as stroke attack, including 55 hemorrhagic stroke patients and 30 ischemic stroke patients; the patients were divided into an observation group of 45 cases and a control group of 40 cases according to data randomization. The control group received routine pre-hospital emergency measures, while the observation group received mild hypothermia treatment in addition to the same routine pre-hospital emergency measures. The two groups of patients continued to receive mild hypothermia treatment for 72 hours after being diagnosed with stroke in the hospital. The National Institutes of Health Stroke Scale (NIHSS), Glasgow Coma Scale (GCS), and Barthel Index Rating Scale (Bathel) scores of two groups of patients were compared before and after treatment.

Results

After 72 hours of mild hypothermia treatment, the NIHSS score and Barthel index of the observation group patients were better than those of the control group patients, and the differences were statistically significant (all P<0.05).

Conclusions

Pre-hospital mild hypothermia treatment for stroke patients can improve the prognosis of neurological function in acute stroke patients.

Key words: Mild hypothermia treatment, Cerebral stroke, Pre hospital first aid

Xin Pan, Xin Wang, Chao Wang, Hui Gu, Min Wu, Jiabo Tang, Hengxi Cui, Zheng Li. Application of mild hypothermia therapy in pre-hospital emergency treatment of stroke[J]. Chinese Journal of Hygiene Rescue(Electronic Edition), 2023, 09(03): 155-158.

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URL: https://zhwsyjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-9133.2023.03.005

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组别	例数	NIHSS评分		GCS评分		ADL评分
组别	例数	治疗前	治疗72 h后	治疗前	治疗72 h后	治疗前	治疗72 h后
观察组	45	16.00±5.02	7.40±3.42^a	8.49±2.37	13.60±2.18^a	24.18±4.91	70.02±10.09^a
对照组	40	15.50±5.96	9.50±3.89^a	8.10±2.33	10.60±2.16^a	23.20±4.58	60.48±9.40^a
t值		0.42	－2.65	0.76	6.36	0.95	4.49
P值		>0.05	<0.05	>0.05	<0.05	>0.05	<0.05

组别	例数	NIHSS评分		GCS评分		ADL评分
组别	例数	治疗前	治疗72 h后	治疗前	治疗72 h后	治疗前	治疗72 h后
观察组	45	16.00±5.02	7.40±3.42^a	8.49±2.37	13.60±2.18^a	24.18±4.91	70.02±10.09^a
对照组	40	15.50±5.96	9.50±3.89^a	8.10±2.33	10.60±2.16^a	23.20±4.58	60.48±9.40^a
t值		0.42	－2.65	0.76	6.36	0.95	4.49
P值		>0.05	<0.05	>0.05	<0.05	>0.05	<0.05

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