To investigated the application effect of combined pre-hospital rescue and Green channel in acute ischemic stroke(AIS) patient treatment.

Patients who definite diagnosis is AIS before or after pre-hospital rescue and Green channel conducting in Emergency department of Drum tower hospital of Nanjing from October 2015 to February 2018 were recruited in present retrospective study. There were 583 patients enrolled in our research. Among them, male is 319 and female is 264.The age range of included patients is 28 to 92 years old, average of age is 69.40±13.35. All patients were divided into observation control group(n=246) which before the institutional implemented and combination therapy group(n=337) which after the institutional implemented. The each timepoint of AIS patient was recorded in the course of diagnosis and treatment. The number cases of intravenous thrombolysis, intravascular interventional therapy, door to needle time(DNT), National Institutes of Health Stroke Scale(NIHSS)scores when admission or discharge, days of hospital stay and prognosis were compared between these two groups.

Since pre-hospital rescue and Green channel were implemented, the amount of intravenous thrombolysis was elevated and the rate of DNT achieving standard (shorter than 60 min)was increased significantly (P<0.01). Compared with observation control group, the time spent in each phase of enroll hospital in combination therapy group was decreased and the number of discharged patient without sequela was increased obviously (P<0.01). However, there was no obvious statistical difference in the cases of intravascular interventional therapy, mortality and days of hospital stay between these two groups (P>0.05).

Application with combined pre-hospital rescue and Green channel improve the procedure of diagnosis and treatment in AIS obviously, shorten DNT effectively and improve AIS patient’s outcome.