To analyze the application value of D-dimer in the etiological diagnosis of high-risk chest pain.

The clinical data of 120 patients with high-risk chest pain diagnosed in our hospital from January 2018 to May 2020 were retrospectively analyzed, including 75 males and 45 females; the average age was (62.43±5.28) years, with range of 44-78 years; the body mass index (BMI) was (18.26-24.37) kg/m², with an average of (21.34±0.98) kg/m². The proportion of acute myocardial infarction, aortic dissection and pulmonary embolism in high-risk chest pain was statistically analyzed. The level of D-dimer in patients with acute myocardial infarction, aortic dissection and pulmonary embolism was measured and compared.

Among the 120 patients with high-risk chest pain, 53 cases had acute myocardial infarction, accounting for (44.17%); 38 cases had aortic dissection, accounting for (31.67%); 29 cases had pulmonary embolism, accounting for (24.16%); the serum D-dimer level in patients with pulmonary embolism was higher than that in patients with aortic dissection and acute myocardial infarction, and the level of serum D-dimer in patients with active venous dissection was higher than that in patients with acute myocardial infarction (P <0.05).

The expression of serum D-dimer in high-risk chest pain caused by different causes is significantly different. Its expression in patients with acute myocardial infarction is low, showing a slight increase, and the rising trend is the most significant in patients with pulmonary embolism. Therefore, the level of D-dimer in patients with high-risk chest pain can be detected clinically to differentiate and diagnose acute myocardial infarction, aortic dissection and pulmonary embolism.